CKiD U25 eGFR calculator
Estimate GFR in children, adolescents and young adults less than 25 years old
If Serum Creatinine is not available, enter '0'
If height is not available, enter '0'
If cystatin C is not available, enter '0'
The CKiD Under 25 (U25) GFR estimating equations were developed and validated with data from the Chronic Kidney Disease in Children (CKiD) Study, a longitudinal study of children, adolescents, and young adults from the United States and Canada with chronic kidney disease (CKD). Glomerular filtration rate (GFR) was measured directly by plasma iohexol disappearance. The equations were derived to estimate GFR using either serum creatinine or IFCC-calibrated cystatin C. In internal validation analysis, these equations outperformed 11 other published equations for estimating GFR in children and young adults with CKD.
- [1]Pierce CB, Muñoz A, Ng DK, Warady BA, Furth SL, Schwartz GJ.: Age- and sex-dependent clinical equations to estimate glomerular filtration rates in children and young adults with chronic kidney disease.Kidney Int. 2021 Apr;99(4):948-956. doi: 10.1016/j.kint.2020.10.047. Epub 2020 Dec 8.
- [2]Ng DK, Pierce CB. : Kidney disease progression in children and young adults with pediatric CKD: Epidemiologic perspectives and clinical applications.Seminars in Nephrology. 2021
Results
Real-time automated computation
The CKiD Under 25 (U25) GFR estimating equations were developed and validated with data from the Chronic Kidney Disease in Children (CKiD) Study, a longitudinal study of children, adolescents, and young adults from the United States and Canada with chronic kidney disease (CKD). Glomerular filtration rate (GFR) was measured directly by plasma iohexol disappearance. The equations were derived to estimate GFR using either serum creatinine or IFCC-calibrated cystatin C. In internal validation analysis, these equations outperformed 11 other published equations for estimating GFR in children and young adults with CKD.
- [1]Pierce CB, Muñoz A, Ng DK, Warady BA, Furth SL, Schwartz GJ.: Age- and sex-dependent clinical equations to estimate glomerular filtration rates in children and young adults with chronic kidney disease.Kidney Int. 2021 Apr;99(4):948-956. doi: 10.1016/j.kint.2020.10.047. Epub 2020 Dec 8.
- [2]Ng DK, Pierce CB. : Kidney disease progression in children and young adults with pediatric CKD: Epidemiologic perspectives and clinical applications.Seminars in Nephrology. 2021