Kt/V from PRU
Quantify hemodialysis adequacy
Result 1 is calculated using the following formula:
Kt/V = (0.026 * PRU) - 0.460
Result 2 is calculated using the following formula:
Kt/V = (0.024 * PRU) - 0.276
Recall that:
Percent Reduction Urea (PRU) = (1 - [postdialysis BUN ÷ predialysis BUN]) X 100%
These equations are frequently used because of their simplicity, and though reasonably accurate, are generally felt to be inferior to the forumula used in our calculator entitled "Kt/V Daugirdas". Although using the PRU is useful as an epidemiologic tool, its utility in individual patients is more limited because of the considerable range of Kt/V that can be seen for any given PRU. Part of this variability is due to the fact that PRU does not take into account urea removal that occurs with ultrafiltration.
- [1]Daugirdas JT.: Rapid methods of estimating Kt/V: three formulas compared.ASAIO Transactions 1990, 36 (3): M362-4
- [2]Lowrie EG, Lew NL.: The urea reduction ratio (URR). A simple method for evaluating hemodialysis treatment. Contemp Dial Nephrol 1992; 12:11.
Results
Real-time automated computation
Result 1 is calculated using the following formula:
Kt/V = (0.026 * PRU) - 0.460
Result 2 is calculated using the following formula:
Kt/V = (0.024 * PRU) - 0.276
Recall that:
Percent Reduction Urea (PRU) = (1 - [postdialysis BUN ÷ predialysis BUN]) X 100%
These equations are frequently used because of their simplicity, and though reasonably accurate, are generally felt to be inferior to the forumula used in our calculator entitled "Kt/V Daugirdas". Although using the PRU is useful as an epidemiologic tool, its utility in individual patients is more limited because of the considerable range of Kt/V that can be seen for any given PRU. Part of this variability is due to the fact that PRU does not take into account urea removal that occurs with ultrafiltration.
- [1]Daugirdas JT.: Rapid methods of estimating Kt/V: three formulas compared.ASAIO Transactions 1990, 36 (3): M362-4
- [2]Lowrie EG, Lew NL.: The urea reduction ratio (URR). A simple method for evaluating hemodialysis treatment. Contemp Dial Nephrol 1992; 12:11.