McMahon Rhabdomyolysis Risk Score

Predict the risk of severe acute kidney injury or mortality in patients with rhabdomyolysis

Age?

Sex?

Initial Calcium <7.5 mg/dL / 1.88 mmol/L?

Initial CK >40,000?

Etiology is seizure, syncope, exercise, statin or myositis?

Initial Phosphate?

Initial Bicarbonate <19 mEq/L?

Initial Creatinine?

About

The McMahon score was developed to predict the risk of severe acute kidney injury or mortality in patients presenting to the hospital with rhabdomyolysis (defined as a serum CPK on admission of >1000 U/L and a peak CPK of >5000 U/L)

The score identifies a low risk population who are unlikely to have severe adverse outcomes including AKI as a result of the injury. The AUC for the final model was 0.82 in the entire cohort.

The score was validated in a follow-up paper by an independent group.

Published Literature & References:

[1]
McMahon GM, Zeng X, Waikar SS.: A risk prediction score for kidney failure or mortality in rhabdomyolysis.JAMA Internal Medicine 2013 October 28, 173 (19): 1821-8
[2]
Simpson JP, Taylor A, Sudhan N, Menon DK, Lavinio A.: Rhabdomyolysis and acute kidney injury: creatine kinase as a prognostic marker and validation of the McMahon Score in a 10-year cohort: A retrospective observational evaluation.European Journal of Anaesthesiology 2016, 33 (12): 906-912

Results

Real-time automated computation

0/2 calculated

Score

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Risk of acute kidney injury requiring renal replacement therapy or death

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Clinical Parameters (0/8)

Medical calculation formulas standardized according to evidence-based clinical protocols.

About

The score identifies a low risk population who are unlikely to have severe adverse outcomes including AKI as a result of the injury. The AUC for the final model was 0.82 in the entire cohort.

The score was validated in a follow-up paper by an independent group.

Published Literature & References:

[1]
McMahon GM, Zeng X, Waikar SS.: A risk prediction score for kidney failure or mortality in rhabdomyolysis.JAMA Internal Medicine 2013 October 28, 173 (19): 1821-8
[2]
Simpson JP, Taylor A, Sudhan N, Menon DK, Lavinio A.: Rhabdomyolysis and acute kidney injury: creatine kinase as a prognostic marker and validation of the McMahon Score in a 10-year cohort: A retrospective observational evaluation.European Journal of Anaesthesiology 2016, 33 (12): 906-912